Secondary Screwworm Fly (Cochliomyia macellaria)

Featured Image. Credit CC BY-SA 3.0, via Wikimedia Commons

Jan Otte

The Revolutionary Science That Stopped a Livestock-Killing Parasite

Insects

Jan Otte

In Texas Hill Country, the Knipling-Bushland U.S. Livestock Insects Research Laboratory in Kerrville has been instrumental in combating the New World screwworm fly (Cochliomyia hominivorax), a parasitic insect once responsible for devastating losses in livestock and wildlife across the United States.

The Menace of the Screwworm Fly

Screwworm larva
Screwworm larva. Tusklike mandibles protruding from the screwworm larva’s mouth rasp the flesh of living warm-blooded animals. A wound may contain hundreds of such larvae. John Kucharski, Public domain, via Wikimedia Commons

The New World screwworm fly poses a unique and deadly threat. Unlike typical parasites, its larvae infest open wounds of warm-blooded animals, consuming living tissue and leading to severe infections, often fatal if untreated. During the mid-20th century, infestations caused significant economic losses in the U.S. livestock industry, with cattle, sheep, and even pets falling victim to this relentless pest.

Pioneering the Sterile Insect Technique


Dr. Edward F. Knipling and Dr. Raymond C. Bushland
1950s. Dr. Edward F. Knipling (seated) and Dr. Raymond C. Bushland in laboratory. USDA National Agricultural Library, Public domain, via Wikimedia Commons

In response to this threat, entomologists Dr. Edward F. Knipling and Dr. Raymond C. Bushland, working at the Kerrville laboratory, developed the groundbreaking Sterile Insect Technique (SIT) in the 1950s. Their method involved mass-rearing screwworm flies, sterilizing them using gamma radiation, and releasing them into the wild. Sterilized males would mate with wild females, resulting in no offspring and a gradual decline in the screwworm population. This environmentally friendly approach proved revolutionary, leading to the eradication of the screwworm fly from the United States by 1966.

Ongoing Vigilance and Research

screwworm
A sterile male Cochliomyia hominivorax, the primary screwworm labeled to study the dispersal, behavior, and longevity. Peggy Greb, Public domain, via Wikimedia Commons

Despite this success, the threat of re-infestation looms, particularly from regions where the screwworm remains endemic. Recent detections of the parasite in southern Mexico have raised alarms, prompting the U.S. Department of Agriculture (USDA) to suspend cattle imports from affected areas and allocate emergency funds to bolster preventive measures. The Kerrville laboratory continues to play a crucial role in these efforts, focusing on refining SIT, enhancing surveillance, and developing new attractants to monitor and control screwworm populations effectively.

A Legacy of Innovation

Sterile Insect Technique
Successful Control of the Mediterranean Fruit Fly in Jordan – “The pupae weight, percent emergence of sterile adult flies and flight ability are checked,” said Ahmad Abu Siam, Supervisor of the SIT Emergence Facility. Sterile Insect Technique (SIT) Emergence Facility, Jordan Valley. 27 April 201.7 IAEA Imagebank, CC BY 2.0, via Wikimedia Commons

The achievements of the Kerrville laboratory extend beyond screwworm eradication. The principles of SIT have been adapted to control other agricultural pests worldwide, showcasing the global impact of the research conducted within this facility. The dedication of scientists like Knipling and Bushland has not only safeguarded the U.S. livestock industry but has also provided a sustainable and environmentally conscious model for pest control globally.

Looking Forward

Sterile Insect Technique
A nuclear technique has helped Senegal suppress the tsetse fly in the Niayes region by 99 per cent, enabling local farmers to significantly increase milk and meat production. The IAEA, in cooperation with the FAO, helped the country to apply the Sterile Insect Technique – a method that uses radiation to sterilize male insects in order to suppress pest populations. The disease that tsetse flies transmit can kill livestock or make them sick. IAEA Imagebank, CC BY 2.0, via Wikimedia Commons

As global trade and climate change continue to influence the movement and survival of pests, the work at the Knipling-Bushland U.S. Livestock Insects Research Laboratory remains as vital as ever. Ongoing research aims to enhance the efficiency of SIT, explore genetic approaches to pest management, and ensure rapid response capabilities to potential outbreaks. The legacy of innovation and dedication at this Kerrville lab serves as a beacon of hope and resilience in the face of evolving entomological challenges.

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